What are Acoustic Reporter Genes (ARGs)? Fluorescent and bioluminescent reporter genes are widely used to study gene expression in cells. But these reporters have limited use in vivo because they are based on light which is very easily scattered by tissue. Ultrasound, on the ...
Every student about to graduate shares the same nightmare: the question “So, what comes next?” For those finishing up an undergraduate education or ending a Master’s program, the answer might be to continue in academia and pursue a PhD. However, if you’re anything like me, the ...
I’ve always been fascinated by the human body and how it works. I used to stay up past my bedtime, poring over my grandparents’ medical textbooks by torchlight under the covers. In high school, I went to all the optional sexual health sessions and reported the intel back to my ...
Have you ever been stuck googling about an antibody that will be essential to your new research project, but unsure which one will mark your target the best, or even which one will work for your application? Like many scientists, I have spent hours sifting through comments and ...
In a lab, you may have heard the phrase gram negative or positive being used to describe a species of bacteria, but what does it actually mean? What relevance does it have on the structure of a bacteria species and how it can be used in a lab? Here we’ll be talking about the ins ...
I didn’t truly address the question of what I wanted to do when I grew up until I was all but finished my undergraduate degree (and I hope I’m not alone in this sentiment). Entering the final semester of a neuroscience major, I was struck with the realisation that I didn’t want ...
The natural CRISPR locus of a bacteria host encodes multiple guide RNAs (gRNAs) on a single array to target the genome of the invading phage pathogen. Over the past decade, CRISPR tools have leveraged such host-defense mechanisms to enable multiplex gene editing in a variety of ...
As a student at Northeastern University, you are expected to spend at least one semester (the majority spend two to three) working in your chosen field. This cooperative education experience (co-op) is what has brought me, a second year bioengineering student, to Addgene. I am ...
