Master plasmid fundamentals, CRISPR techniques, AAV serotype selection, and antibody applications. Written by scientists, for scientists.
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In July, Addgene hosted a webinar titled “CRISPR Pooled Libraries: Optimizing Knockout Library Design.” If you missed it, don’t worry! Not only is it still available to watch, but this post covers the same material.
Every few months we highlight some of the new plasmids, antibodies, viral preps, and more in the repository through our Hot Plasmids articles. This month, we’ve got lots of exciting materials to talk about, from the latest prime editors and new CRISPR tools to antibodies and a ...
Every August, the CRISPR community returns to Cold Spring Harbor Laboratory for the Genome Engineering: CRISPR Frontiers conference. This year’s meeting gathered researchers across the field, from the bacteriophage-defense biology that revealed these systems to clinical research ...
If you came to Addgene looking for a plasmid sequence and ran into a login request instead, we understand why that’s frustrating. You knew exactly what you needed, and now there’s one more step between you and the information you’re looking for. We didn’t add this step to slow ...
Over 75,000 pathogenic genetic variants have been identified in humans and cataloged in the ClinVar database. Previously developed genome editing methods using nucleases and base editors have the potential to correct only a minority of those variants in most cell types. But ...
Each plasmid in Addgene’s collection contains a story, hidden in the wealth of data all plasmids come with. The story tells who made the plasmid, who is using it, where it comes from and where it’s going, what it does, and even what advancements it has helped make.
As co-founder Melina Fan, PhD, transitions to Chief Scientific Advisor, we reflect on the problem she set out to solve 20 years ago, the community she helped build, and where she and Addgene go next.
Modeling is not just a job for humans — it is also a job for many different organisms. And like human modeling, biological modeling turns out to be surprisingly glamorous and diverse. But what comes to mind when you picture a “model organism”? A mouse? A pesky fruit fly? ...
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