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This article was written by Alyssa Cecchetelli and Andrew Hempstead. What do smell, taste and sight have in common, besides being one of the five senses? GPCRs or G-protein-coupled receptors (GPCRs)! Aside from these three senses, GPCRs play roles in initiating signaling ...
Optogenetics is a neuroscience method that lets you fire neurons with the flick of a light switch. Neurons are not typically persuaded to fire when light is shined on them, but the expression of light-gated ion channels such as channelrhodopsins (ChRs) makes them ...
Over the past decades, neuroscientists have made great strides to map brain regions and allocate specific functions to them. Electrical recordings and lesioning studies have been essential for this task. However, most lesioning methods destroy areas larger than intended and may ...
The aim of behavioral neuroscience is to define brain areas that are linked to a certain behavior. It is a very old branch of science, dating back several hundred years, with historical ties to psychology and philosophy (the mind-body problem). Because of the availability of ...
This post was contributed by Patrick Miller-Rhodes, a Ruth L. Kirschstein NRSA Predoctoral Fellow at University of Rochester Medical Center. During development, complex genetic programs specify and assemble diverse arrays of neurons, forming the neuronal circuits that will later ...
Stochastic multicolor labeling is a popular technique in neuroscience and developmental biology. This type of cell labeling technique involves the introduction of a transgene construct containing fluorescent proteins (XFP) of different colors to label an organ or entire ...
The central nervous system (CNS) orchestrates complex processes enabling organisms to control their movements and behavior. These functions and others are controlled by collections of neurons that are intricately wired into circuits through synaptic connections (Shepherd, 2004). ...
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