New Neuroscience Tool: The iGluSnFR3 Glutamate Sensor

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GPCR signaling schematic shows ligand binding the receptor which interacts with the gamma, beta, and alpha subunits below. These subunits split off when activated and results in a cellular response
Graphic of channelrhodopsin activated with blue light. Without light, the channelrhodopsin is inactive, no ions flow in, and neurons don't fire. With blue light, the channelrhodopsin opens and allows an influx of ions into the neuron. This results in neuronal firing.
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