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Negative Can Be Positive: Open AAV Data with Addgene

By Jason Nasse

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Recent Posts

Viral Vectors

AAV Q&A with Tim Miles

Guest Blogger May 17, 2022

Did you catch our April AAV webinar with Tim Miles, PhD, Director of the CLOVER Center at CalTech? If so, you may have submitted a question that didn’t get answered live - but he kindly took some time to address all your unanswered questions via text! (well, maybe not all of ...

CRISPR

Adenoviral Delivery of CRISPR/Cas9 Aims to Expand Genome Editing to Primary Cells

Kendall Morgan December 10, 2020

Originally published Sep 30, 2014 and last updated Dec 10, 2020 by Benoit Giquel.   Adenoviral vectors (AdVs) have been used for many years for in vivo delivery and gene therapy and represent one of the most studied viruses. Adenoviruses are non-enveloped double-strand DNA ...

Viral Vectors

Adenoviral Vector Production and Troubleshooting

Karen Guerin June 14, 2018

Adenoviral vectors (AdV) are attractive vectors for research applications and gene therapy: they can be produced at high titers, can accommodate large transgenes, transduce quiescent and dividing cells, and do not integrate into the host’s genome. The main challenge with using ...

Adenovirus production

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