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Viral Vectors 101: Chemogenetics

By Multiple Authors

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Recent Posts

Optogenetics

Tagging Optogenetics and Chemogenetics Receptors: Fluorescent Proteins and Other Options

Guest Blogger May 11, 2021

This post was contributed by Adriana Galvan, an associate professor at Emory University School of Medicine. Optogenetics and chemogenetics are powerful tools to modulate the activity of neurons and other brain cells. Since the opsins or chemogenetic receptors used in these ...

Electron micrograph showing hM4Di tagged with mCherry remaining cytoplasmic and hM4Di-HA tag localizes to the plasma membrane.
Chemogenetics

GPCRs: How Do They Work and How Do We Study Them?

Various Addgenies February 11, 2021

This article was written by Alyssa Cecchetelli and Andrew Hempstead. What do smell, taste and sight have in common, besides being one of the five senses? GPCRs or G-protein-coupled receptors (GPCRs)! Aside from these three senses, GPCRs play roles in initiating signaling ...

GPCR signaling schematic shows ligand binding the receptor which interacts with the gamma, beta, and alpha subunits below. These subunits split off when activated and results in a cellular response
Optogenetics

Chemogenetics vs. Optogenetics: Which Method Should I Choose?

Maya Peters Kostman June 11, 2020

Chemogentic and optogenetic technologies have pushed the boundaries in neuroscience by granting targeted control over neuronal activity. While they serve similar purposes, both techniques offer researchers different advantages and limitations. The four main factors in which ...

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