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Chemogenetics vs. Optogenetics: Which Method Should I Choose?

Posted by Maya Peters Kostman on Jun 11, 2020 9:34:59 AM

Chemogentic and optogenetic technologies have pushed the boundaries in neuroscience by granting targeted control over neuronal activity. While they serve similar purposes, both techniques offer researchers different advantages and limitations. 

The four main factors in which chemogenetics and optogenetics differ are:

  • Timing
  • Targeted manipulation
  • Controlling stimulation
  • Invasiveness 

Choosing the best set of tools therefore depends on what you are looking to study.

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Topics: Optogenetics, Viral Vectors, Chemogenetics

Viral Vectors 101: Chemogenetics

Posted by Maya Peters Kostman on May 14, 2020 9:15:00 AM

In order to understand the complex wiring of the brain and the underpinnings of neurological disease, neuroscientists need to be able to probe cells and circuits without disrupting normal brain function. Chemogenetics has become a popular tool in the field as it provides a noninvasive method for manipulating cell activity, especially neuronal firing.

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Topics: Viral Vectors, Viral Vectors 101, Chemogenetics

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