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Tagging Optogenetics and Chemogenetics Receptors: Fluorescent Proteins and Other Options

By Guest Blogger

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Recent Posts

Chemogenetics

GPCRs: How Do They Work and How Do We Study Them?

Various Addgenies February 11, 2021

This article was written by Alyssa Cecchetelli and Andrew Hempstead. What do smell, taste and sight have in common, besides being one of the five senses? GPCRs or G-protein-coupled receptors (GPCRs)! Aside from these three senses, GPCRs play roles in initiating signaling ...

GPCR signaling schematic shows ligand binding the receptor which interacts with the gamma, beta, and alpha subunits below. These subunits split off when activated and results in a cellular response
Optogenetics

Chemogenetics vs. Optogenetics: Which Method Should I Choose?

Maya Peters Kostman June 11, 2020

Chemogentic and optogenetic technologies have pushed the boundaries in neuroscience by granting targeted control over neuronal activity. While they serve similar purposes, both techniques offer researchers different advantages and limitations.  The four main factors in which ...

Viral Vectors

Viral Vectors 101: Chemogenetics

Maya Peters Kostman May 14, 2020

In order to understand the complex wiring of the brain and the underpinnings of neurological disease, neuroscientists need to be able to probe cells and circuits without disrupting normal brain function. Chemogenetics has become a popular tool in the field as it provides a ...

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