In this episode of the Addgene Podcast, we introduce you to the Journal of Emerging Investigators, an open-access journal that enables high school students to publish peer-reviewed scientific research. You’ll meet some of the folks behind the journal and hear from a fantastic team of high school students who recently submitted to the journal with funding from Addgene.

This guest post was contributed by Ally Huang is a 4th year PhD student at MIT.

While I had always enjoyed learning about biology in high school, it wasn’t until I started working in my first molecular biology lab in college that I really fell in love with it. Something about being able to actually hold all those seemingly abstract biological reactions that I learned about from textbooks just made everything click in my head and left me thinking: I wish I had this kind of experience earlier!

This guest post was contributed by Marco Straccia, an Associate Professor at University of Barcelona.

The challenge: Making courses on genetic manipulation more hands on

While teaching courses about gene therapy and genetic manipulation, I and other professors at the University of Barcelona wanted to develop strategies to make our classes more practical and hands-on. Students in these courses get plenty of theory in their lectures, but it can be difficult to determine how much information they’ve absorbed if they don’t get a chance apply it in an interactive setting.

Scientists routinely use techniques to alter gene expression or to label specific cells, but there are too few resources to teach students how to perform these experiments in the beginning. In most classrooms, the laboratory experience is focused on classical embryology techniques such as basic observation and dissections. Students don’t usually perform more modern techniques used in genetics or molecular biology because the experiments are either not accessible or too challenging for amateur scientists. Planarians, wormy creatures commonly found in freshwater ponds, provide a good potential solution to this problem. Planarians are easy to buy, cultivate, and have interesting phenotypes to study. In addition, the Sánchez lab has made it easier to perform advanced developmental biology experiments in planarians with their recent plasmid deposit.

This post was contributed by Tim Herman, director of the MSOE center for BioMolecular Modeling and the CEO of 3-D Molecular Designs.

Have you ever held your favorite protein in the palm of our hand? Well, actually – have you ever held a model of your favorite protein in your hand? At 3D Molecular Designs, we create physical models of proteins using 3D printing technology. The tagline for our company is “…where molecules become real”.  We sometimes forget that the models we create are around 30 million times larger than the real thing. Nevertheless, the models are compelling, and I encourage you to hold one.