By Susanna Stroik
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By Justin Ng and Alyssa Cecchetelli Science is a constantly evolving and demanding field, requiring a variety of biological and molecular tools. One such tool is the model organism, an essential aspect of biological research that has defined our understanding of biological ...
This post was contributed by Katherine Rogers, a postdoctoral researcher at the Friedrich Miescher Lab of the Max Planck Society. Zebrafish (Danio rerio) have been used since the 1930’s in a range of biological studies, including investigations into environmental pollutants and ...
In Part 1 of our mouse modeling blog series, we covered techniques that can be used to introduce genetic modifications into mouse embryos. But once you generate a growing colony of genetically engineered mice, what can you do? In this post, we’ll cover why and how to cross mice ...
Optogenetics, the use of light sensitive proteins (opsins) to manipulate cell activity, enables researchers to silence or incite neuronal firing and study subsequent effects on behavior. The system is an especially powerful tool for in vivo behavioral studies because it is ...
Mice are a common model organism used to understand mammalian traits and genetically engineered mouse models provide researchers with useful and adaptable tools to perform basic and preclinical research. For scientists new to using mouse models, the possibilities may seem ...
In this heyday of molecular biology, many scientists do a lot of DNA work but never get to actually manipulate the organism they study (unless if you count normal human interaction for all of us studying human genes in test tubes and gels). As a freshman in college I studied ...
By Alyssa Cecchetelli and Lukas Morgan Model organisms are vital tools used by researchers around the globe. These organisms share many genes with humans, are easily maintained in the lab, and have short generation times that make it easy to study the effects of genetic ...
