By Aliyah Weinstein
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We are excited about our new partnership with Allele Biotechnology which allows researchers to deposit plasmids containing the fluorescent protein mNeonGreen. This fluorescent protein joins mTFP1 and mWasabi, as fluorophores from Allele Biotechnology that now can be deposited at ...
This post was contributed by guest blogger, Eugenia Rojas. A question worthy of a PhD: How do you visualize protein turnover within a neuron? For my PhD I studied a synaptic protein that is linked to neurodegeneration. The level of this protein is decreased in Alzheimer’s ...
This post was contributed by Doug Richardson, Director of the Harvard Center for Biological Imaging and a Lecturer on Molecular and Cellular Biology at Harvard University. No matter whether you are a sports photographer at the Super Bowl, a medical technologist taking an x-ray, ...
This post was contributed by guest blogger, Luke Lavis, a Group Leader at the Janelia Research Campus, Howard Hughes Medical Institute. Chemistry is dead, long live chemistry! The discovery of green fluorescent protein (GFP) sparked a renaissance in biological imaging. Suddenly, ...
Since the first research applications of GFP were published in the 1990s, biologists have spent a lot of time making things glow. Chances are you’ve used a GFP derivative to conduct subcellular localization studies or make a reporter construct. Fluorescent proteins (FPs) are ...
This post was contributed by Jae Lee and Pantelis Tsoulfas of the Department of Neurological Surgery at the University of Miami. The beginning of this century has seen some major advances in light microscopy, particularly related to the neurosciences. These developments in ...
CRISPR-Cas9 genome editing may be the hot new way to manipulate gene expression, but other gene manipulation systems remain valuable to biology. Cre-lox recombination, discovered in the 1980s, is one of the most important ways to spatially and temporally control gene expression, ...