By Guest Blogger
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One of the biggest barriers to gene therapy treatment of central nervous system (CNS) diseases is the blood brain barrier (BBB). It’s the BBB’s job to block the entry of pathogens to the CNS, but this also stops viral vectors, such as adeno-associated virus (AAV), from reaching ...
The C. elegans community has always emphasized the need for open science and collaboration. The field already has comprehensive reference pages and curated databases for scientists including Wormbook, Wormatlas and Wormbase. And scientists have been continuously sharing their ...
Optogenetics, the use of light sensitive proteins (opsins) to manipulate cell activity, enables researchers to silence or incite neuronal firing and study subsequent effects on behavior. The system is an especially powerful tool for in vivo behavioral studies because it is ...
Mice are a common model organism used to understand mammalian traits and genetically engineered mouse models provide researchers with useful and adaptable tools to perform basic and preclinical research. For scientists new to using mouse models, the possibilities may seem ...
As a person with many roles and responsibilities, I have to think a lot about how to balance those roles. I’m a father of three, a scientist and science communicator, and I strive to be a volunteer and contribute to my community. This past year, I spent some time thinking about ...
This post was contributed by Patrick Miller-Rhodes, a Ruth L. Kirschstein NRSA Predoctoral Fellow at University of Rochester Medical Center. During development, complex genetic programs specify and assemble diverse arrays of neurons, forming the neuronal circuits that will later ...
Microbiome studies have traditionally fallen into studies of who’s there and what are they doing. To address these questions, biologists often use next-generation sequencing. Sequencing the 16S rRNA reveals the identity of the organisms present while sequencing of all ...
