Master plasmid fundamentals, CRISPR techniques, AAV serotype selection, and antibody applications. Written by scientists, for scientists.
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We’ve all heard “Get that tube on ice!!” and “I hope it isn’t degraded” when scientists talk about their precious RNA samples. RNA is inherently less stable than most macromolecules used in scientific research such as DNA or protein. It comes as no surprise then that stability ...
This post was originally written by Joel McDade and significantly updated in 2022 by Susanna Stroik. The advent of CRISPR/Cas9 has made it easier than ever to make precise, targeted genome modifications. Cas9 has been modified to enable researchers to knock out, knock in, base ...
Every few months we highlight a subset of the new plasmids, antibodies, and viral preps in the repository through our hot plasmids articles. Think we missed something hot? You can pitch a Hot Plasmids section (antibodies and viral preps welcome!) here.
Welcome to our deep dive series, which aims to increase your understanding and technical proficiency with common applications - now let’s dive right in!
We're going virtual for Addgene’s first AAV Data Hub Challenge, now taking place Dec. 6, 2022! Share your AAV data, connect with other researchers working with AAV, support open science, and maybe even win a $500 travel prize in our open data extravaganza!
Welcome to the last of our Summer SciComm Series! We hope you've enjoyed this small glimpse into the world of science communication and can use what you've learned to share your science with others. My favorite quote about science ever comes from an interview in which someone ...
Working with AAV vectors in the brain and peripheral nervous system presents a special challenge to scientists. What works well in one cell or neuron type may not work well for a neighboring cell type, even within the same brain region or nucleus. Just optimizing AAV expression ...
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