Master plasmid fundamentals, CRISPR techniques, AAV serotype selection, and antibody applications. Written by scientists, for scientists.
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You’ve acquired your long-awaited data – and it looks great! There are some exciting trends in your experimental groups, but how do you determine if they deserve that oh-so coveted asterisk of significance? You’ve already done the heavy lifting, so don’t let the statistical ...
Much of today's biological research requires a close examination of specific proteins within a system. This can be pretty complicated given that a single cell has tens of thousands of proteins functioning in a variety of ways. How do scientists focus on the activity or function ...
Since its early years, the light microscope has been a powerful tool in almost all disciplines. In biology, innovative new imaging approaches are constantly being developed which combine computational processing with biological protocols and revolutionary physical approaches. ...
Addgene saw big changes in 2022, from the launch of a new material to the redesign of a community resource. Now that we’re in the first quarter of the new year, I’d like to take a moment to reflect on our accomplishments from 2022 and share what we’re looking forward to in 2023 ...
This post was co-authored by Susanna Stroik and Rachel Leeson. Here at Addgene, we like to help share useful new resources with the scientific community – particularly ones that help address ongoing problems, like cells lines. A 2014 study in Science found that approximately ...
Turn it on? Turn it off? Turn it down, but not forever? You don’t need to resort to the force to control protein expression in mammalian cells: easy to use biological tools are abundant! In this post, we will review tried-and-true protein expression control tools as well as ...
When Karl Barry Sharpless was awarded this year’s Nobel Prize in Chemistry, he joined an elite club, becoming just the fifth repeat Nobel Prize winner in history. Interestingly, he also adds to the disproportionately large number of honorees to have trained under a previous ...
