X-CHIME: Context Dependent Germline Knockout in Immune Cells

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A protein ribbon model of nLightG and nLightR (a) and microscopy images showing expression of nLightG in cultures with NE and not in cultures without NE. The same experiments are repeated with nLightR, but there is faint expression in the cultures w/o NE.
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Map displaying location of Addgene's booth, 3422
Schematic of a human body with cartoons indicating systemic therapy (via IV); patient-derived editing ex vivo (via cell culture); and allogenic therapy (via cells derived from another person).

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