Every few months we highlight a subset of the new plasmids, antibodies, and viral preps in the repository through our hot plasmids articles. Think we missed something smokin'? You can pitch a Hot Plasmids section (antibodies and viral preps welcome!) here.
Originally written by Marcy Patrick and Mary Gearing on Mar 12, 2015; updated by Christina Mork, Jul 27, 2020; updated by Susanna Stroik January 24, 2023. DNA damage drives genome instability and contributes to cancer, premature aging, and other harmful processes. The most ...
Promoters control the binding of RNA polymerase and transcription factors. Since the promoter region drives transcription of a target gene, it therefore determines the timing of gene expression and largely defines the amount of recombinant protein that will be produced. Many ...
This post was originally written by Melina Fan and updated Nov 3, 2022 by Susanna Stroik. You’ve designed your gRNA and introduced it into your target cells with Cas9. Hooray! Now it’s time to make sure your genome edits went according to plan. In this blog post we’ll explain ...
This post was originally written by Joel McDade and significantly updated in 2022 by Susanna Stroik. The advent of CRISPR/Cas9 has made it easier than ever to make precise, targeted genome modifications. Cas9 has been modified to enable researchers to knock out, knock in, base ...
Every few months we highlight a subset of the new plasmids, antibodies, and viral preps in the repository through our hot plasmids articles. Think we missed something hot? You can pitch a Hot Plasmids section (antibodies and viral preps welcome!) here.
This post was originally written in 2014 by Kendall Morgan and updated in 2022 by Lucie Wilson. Lucie is an Addgene co-op from Northeastern University. There can be no doubt that CRISPR/Cas9 technology has been a breakthrough for the genome-editing field. It has the possibility ...
Every few months we highlight a subset of the new plasmids and viral preps in the repository through our hot plasmids articles. These articles provide brief summaries of recent plasmid deposits and we hope they'll make it easier for you to find and use the plasmids you need. If ...
