Mice are a common model organism used to understand mammalian traits and genetically engineered mouse models provide researchers with useful and adaptable tools to perform basic and preclinical research. For scientists new to using mouse models, the possibilities may seem ...
Apoptosis or “programmed cell death" plays a pivotal role in an array of biological processes including development, the immune system, and cell turnover. Apoptosis is a highly controlled process that is triggered by internal and external signals such as developmental cues and ...
In this heyday of molecular biology, many scientists do a lot of DNA work but never get to actually manipulate the organism they study (unless if you count normal human interaction for all of us studying human genes in test tubes and gels). As a freshman in college I studied ...
By Alyssa Cecchetelli and Lukas Morgan Model organisms are vital tools used by researchers around the globe. These organisms share many genes with humans, are easily maintained in the lab, and have short generation times that make it easy to study the effects of genetic ...
This post was contributed by Bárbara Pinho, a science communicator at the Portuguese science museum "Fábrica Centro Ciência Viva" in Aveiro, Portugal. If cancer was a musician, then metastasize is touring. But you know what a touring musician needs? A backstage team. Meet the ...
For the last 14 years, scientists have been coming to the Addgene website in search of plasmids. Now, scientists are beginning to see Addgene as a large data set. Addgene has over 65,000 plasmids in the repository, each verified by sequencing, which makes the repository a ...
This post was contributed by Kusumika (Kushi) Mukherjee. The ultimate goal in the field of regenerative medicine is to replace lost or damaged cells. Here, I will discuss the two major processes by which an adult somatic cell is converted to a different cell type for ...
This post was contributed by Kusumika (Kushi) Mukherjee, editor of Trends in Pharmacological Sciences, a Cell Press reviews journal. Stem cells are special types of cells that can develop or “differentiate” into more specialized cells with specific functions [1]. In many ...
