Rachel is a Science Communications Specialist at Addgene. She manages the blog and social media.
We are excited to announce the fourth edition of our popular eBook, Plasmids 101, is now available!
Viruses are simple: a genome packaged in a protein shell (Taylor, 2014). They’re so simple that we can’t even decide if they’re alive or not. Yet these simple, small particles have quite the outsized impact — and not just on the disease front.
If you’ve ever used Golden Gate Assembly for cloning, you might be familiar with the rules of thumb for designing your overhang sets. But are those rules the best way to design GGA overhang sets, particularly for high-complexity reactions?
If you study proteins, you’re probably quite interested in the canonical 20 amino acids. But in your quest to learn more about your protein of interest, you may find the available amino acids a bit…limiting. It may be time, then, to look towards genetic code expansion (GCE): ...
Addgene is excited to announce the launch of our partnership with the Institute for Protein Innovation (IPI). Together, we’ll be working to provide researchers with a collection of IPI’s well-validated and ready-to-use recombinant antibodies. The first collection, a set of ...
IBEX is a highly multiplexed tissue imaging method that uses iterative staining and chemical bleaching to allow for high-resolution imaging without degrading the tissue (Radtke et al., 2020, 2022). I do mean highly multiplexed: you can image over 65 different parameters using ...
Last summer, we posted about our bioinformatics quest, which led us to Seqera Labs, a company that provides open source workflow orchestration software for data pipeline processing (Nextflow), cloud infrastructure, and secure collaboration.
When it comes to using antibodies in the lab, we focus on a lot on the variable domain and not so much on the constant, or Fc, domain. Sure, we all know that the Fc domain provides structure, determines isotypes, and provides a place for secondary antibodies to bind. We also ...
