Fighting with antibodies to produce immunohistochemistry images that are crisp, bright, and lacking in non-specific staining can be a challenge in the best of cases. But it can be particularly challenging when your only antibody option is from the same species as your tissue ...
I spent about seven years working in research labs, and then pivoted to writing full-time in mid-2020. As I left the ivory tower and walked down into its foothills, I began to have conversations with many people who eagerly follow progress in synthetic biology, and want to be ...
Running a Western blot can be a bit daunting for first-timers. That's why we gave our written protocol a video companion! Follow along as Addgenie Meghan and Abi run a Western blot and share tips for this tricky application.
Welcome to our deep dive series, which aims to increase your understanding and technical proficiency with common applications - now let’s dive right in!
In a lab, you may have heard the phrase gram negative or positive being used to describe a species of bacteria, but what does it actually mean? What relevance does it have on the structure of a bacteria species and how it can be used in a lab? Here we’ll be talking about the ins ...
It is a well known fact if a multicopy variant of a gene exists, there must be assays that researchers can use to quantify said copies. They do so using copy number variation (CNV) assays. There are several varieties of these, but in this blog post, we're going to focus on ...
Chromatin immunoprecipitation (ChIP) is an extremely useful technique that provides insight into protein:DNA interactions. ChIP works by using antibodies to capture protein:DNA complexes with antibodies specific to your protein(s) of interest. Once the complex is captured, it is ...
What is the universal thing that unites all scientists? Curiosity? Passion? A love of learning? No. Or at least not entirely. What truly unites us all is the frustration of an experiment failing because of a small, avoidable mistake. Or worse, when you're trapped in a pattern of ...
