Master plasmid fundamentals, CRISPR techniques, AAV serotype selection, and antibody applications. Written by scientists, for scientists.
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The central dogma in molecular biology is DNA→RNA→Protein. To synthesize a particular protein DNA must first be transcribed into messenger RNA (mRNA). mRNA can then be translated at the ribosome into polypeptide chains that make up the primary structure of proteins. Most ...
Why study neural connectivity? One of the early lessons many of us learned in biology is that the body’s architecture and plumbing are important. We started with learning the head is connected to the neck. Shortly after, we learned about organs and the jobs they perform. This ...
Scientists routinely use techniques to alter gene expression or to label specific cells, but there are too few resources to teach students how to perform these experiments in the beginning. In most classrooms, the laboratory experience is focused on classical embryology ...
This post was contributed by guest blogger Clare O'Connor an Associate Professor at Boston College. National reports stress the importance of providing authentic research experiences to undergraduate students (1, 2), but educators face significant challenges in designing ...
Last Wednesday we worked with the Harvard GSAS Science Policy Group to organize a Minisymposium on Reproducibility. The minisymposium focused on solutions to reproducibility issues in the biological sciences and featured speakers from academia, industry, nonprofits, and ...
This post was contributed by guest blogger Talley Lambert, a Research Associate at Harvard Medical School. The need for a community fluorescent protein database As recognized by the 2008 Nobel Prize, fluorescent proteins (FPs) have become one of the most indispensable tools in ...
Every few months we highlight a subset of the new plasmids in the repository through our hot plasmids articles. These articles provide brief summaries of recent plasmid deposits and we hope they'll make it easier for you to find and use the plasmids you need. If you'd ever like ...
