Master plasmid fundamentals, CRISPR techniques, AAV serotype selection, and antibody applications. Written by scientists, for scientists.
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Injections in mice are a day-to-day task for many labs. Deciding which type of injection to use depends on a number of factors. You have to weigh the pros and cons of various methods and choose what is best for you — and the mice. While not an exhaustive list, these can include ...
One of the most pivotal decisions many PhDs face when transitioning from academia to industry is whether to stay hands-on in the lab or pivot to a managerial role. For those contemplating the leap into management, the journey can be as exciting as it is challenging.
A viral vector that can target specific tissues, even when administered systemically, without causing disease? Recombinant adeno-associated viral vectors, or rAAVs, can sound almost too good to be true! In a previous post, we covered systemic capsids, which allow AAVs to broadly ...
Over 75,000 pathogenic genetic variants have been identified in humans and cataloged in the ClinVar database. Previously developed genome editing methods using nucleases and base editors have the potential to correct only a minority of those variants in most cell types. But ...
AAV Packaged on Request, an expansion of our viral vectors service, has officially launched! As of today, you can request any of over 3,000 eligible AAV cargo plasmids in the Addgene repository to be packaged in your choice of five different serotypes.
Every year, we like to add in some holiday cheer to our blog and social media. This year, we're doing so through the twelve days of antibodies. We hope you enjoy it, and we wish you a great 2025!
Addgene is ending 2024 with big plans for our future. And while we’ve been excited to share them with you, we realized our 20th anniversary was about all the amazing years behind us, as much as it as about the amazing years in front of us. So in our last celebratory moment, we ...
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