Master plasmid fundamentals, CRISPR techniques, AAV serotype selection, and antibody applications. Written by scientists, for scientists.
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This post was contributed by Kutubuddin Molla, a Fulbright Visiting Scholar at the Pennsylvania State University. Imagine you are dealing with a defective gene, Xm, the sequence of which is identical to the correct gene, Xw, except for a single base. If you heard about CRISPR, ...
This post was contributed by Kelly Hills, founding bioethicist of Rogue Bioethics. On November 25, the MIT Technology Review dropped a bombshell report. A scientist working in China was using CRISPR/Cas9 in an attempt to create gene-edited babies. Several hours later, the ...
In this quarterly blog series, we’ll highlight a few of the new CRISPR plasmids available at Addgene. We will still periodically focus on specific CRISPR plasmid tools more in-depth, but we hope that this blog series will help you find new CRISPR tools for your research.
By now you have probably heard about Addgene’s viral service but did you know that Addgene also performs independent research? Since launching the viral service in 2016 Addgene’s research team has been actively investigating ways to improve viral vector production. Whether ...
Before I started writing for the Addgene blog, sharing Chemistry Cat memes was how I used social media as a scientist. I mean, I had a LinkedIn page and a Twitter handle, but I wasn’t using them to my professional advantage. It wasn’t until I wrote a blog post about a research ...
Every few months we highlight a subset of the new plasmids in the repository through our hot plasmids articles. These articles provide brief summaries of recent plasmid deposits and we hope they'll make it easier for you to find and use the plasmids you need. If you'd ever like ...
Last updated Apr 17, 2020. Before being adapted by scientists to edit the genome of virtually any organisms on this planet, CRISPR-Cas systems were merely adaptive immune systems that provide bacteria protection against infectious agents. Several enzymes behind this immunity ...
