By Alyssa Shepard
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If you're an international researcher who uses plasmids containing genes from rabies and vesicular stomatitis virus, you may have noticed it’s been easier to order these plasmids. This is because in 2024 certain export control exceptions were made by the US Bureau of Industry ...
Forward genetics screens are a valuable part of the molecular biology toolbox to identify new target genes for drug discovery or to understand the intricacies of molecular pathways. These screens have gotten larger, easier, and more comprehensive thanks to the consistent ...
Bundling up for winter? The weather outside might be frightful, but browsing the 49 new preps available in the Addgene viral vector repository with a nice cup of hot chocolate is absolutely delightful. Grab a hot beverage and a blanket, then scroll on for some wintery delights!
We recently updated our blog post on Prime Editing, and that meant rereading many of the original papers reporting various prime editing tools. These papers are chock full of great tips to guide your experimental design, especially the design of the RNA sequences you’ll use in ...
Injections in mice are a day-to-day task for many labs. Deciding which type of injection to use depends on a number of factors. You have to weigh the pros and cons of various methods and choose what is best for you — and the mice. While not an exhaustive list, these can include ...
One of the most pivotal decisions many PhDs face when transitioning from academia to industry is whether to stay hands-on in the lab or pivot to a managerial role. For those contemplating the leap into management, the journey can be as exciting as it is challenging.
A viral vector that can target specific tissues, even when administered systemically, without causing disease? Recombinant adeno-associated viral vectors, or rAAVs, can sound almost too good to be true! In a previous post, we covered systemic capsids, which allow AAVs to broadly ...
