Addgene’s viral vector services allow scientists to conduct experiments faster, skipping the preparation steps of production, purification, and titering. Our newest viral vector service, AAV Packaged on Request has seen a fantastic response from the research community. Customers have taken advantage of the customizability, choosing the cargo, serotype, and prep size they need for their experiments — and we’ve been able to ship them out in record time.
However, our in-stock preps remain a popular choice thanks to the convenience of smaller sizes and quick shipping. We continue to expand the collection to meet the diverse needs of our community and support a wide range of experimental designs. Here are nine great additions, including our first far-red fluorescent marker, a Flp-dependent channelrhodopsin in the retrograde serotype, and a dTomato under the control of the E6 regulatory element, which targets it to VIP cortical interneurons.
Take a look to see if these new preps might enhance your research!
Table 1: New ready-to-use viral vectors in the Addgene repository
| Name | Serotype | Category | Depositor | Notes |
| pAAV-CAG-emiRFP670 | AAV1 | Control | Kiryl Piatkevich | New viral tool |
| pAAV-S5E6-dTom-nlsdTom | AAV1 | Control | New serotype | |
| pAAV_hSyn-PdCO-mScarlet-WPRE | AAV1 | Optogenetics | Ofer Yizhar |
New viral tool |
| pAAV-Ef1a-fDIO hChR2(H134R)-EYFP | AAVrg | Optogenetics | Karl Deisseroth | New viral tool |
| AiP13987: pAAV-AiE0452h_3xC2-minBG-jRGECO1a-WPRE3-BGHpA | PHPeB | Biosensor | New viral tool | |
| PHPeB | Biosensor | New viral tool | ||
| AiP14361: pAAV-AiE0452h_3xC2-minBG-jGCaMP8s-WPRE3-BGHpA | PHPeB | Biosensor | New viral tool | |
| pGP-AAV-CAG-FLEX-jGCaMP8m-WPRE | AAV5 | Biosensor | GENIE Project | New serotype |
| pENN.AAV.CMVs.Pl.Cre.rBG | AAV5 | Recombinase | James M. Wilson | New serotype |
AAVrg = AAV retrograde (also called AAV2-retro)
Looking for more viral vectors? Browse our in-stock viral vectors or consider our AAV Packaged on Request service, which offers over 3,000 eligible transfer plasmids and five different serotypes. Not sure what to request? Addgene's Data Hub can help, with over 100 user-submitted viral vector reports. And don't forget to use the link below to keep up with the latest in Addgene's viral vector services and resources!
This blog post was written by Brook Pyhtila and Brian O'Neill.
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Topics: Viral Vectors, AAV, Addgene’s Viral Service
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