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A History of Genome Engineering in Popular Culture

Posted by Guest Blogger on Feb 25, 2020 9:15:00 AM

This post was contributed by Kartik Lakshmi Rallapalli, a graduate student at the University of California, San Diego.

The revolution in genetic engineering techniques is a speculation of yesteryear which has been realized recently. Science Fiction (SciFi) writers have been curious about the capability of transforming the genetic code of living organisms and its societal implications even before the discovery of genes themselves. 

How has scientific progress in genetic editing impacted the world of fiction and vice versa? We draw a parallel between the timelines of the scientific advancements and the noteworthy work of fiction that it inspired. CAUTION: Spoilers alert!

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Topics: Genome Editing, Plasmids

Binning Singletons: Tackling Conference Networking When You Don’t Know Anyone

Posted by Guest Blogger on Feb 18, 2020 9:15:00 AM

This post was contributed by Joe James from Binning Singletons.

The sheer scale of a large conference can be intimidating. And it can be exacerbated when everyone seems to know one another, but they don’t know you. First time attendees and those attending alone often feel this even more, because they don’t have the networks or experience to get the most of meeting

I experienced this at the ASM General Meeting (now Microbe) in 2013 in Denver, CO. While I had been to the General Meeting seven other times I had subsequently changed fields and my cohort of friends and colleagues had moved on as well, so I knew very few people. I didn’t really fit in anywhere and everyone who was doing the kind of work my lab wanted to do already seemed to know each other and what to do. 

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Topics: Science Careers, Networking, Conferences, Early Career Researcher

The Many Reasons for Irreproducible Research- and a Vaccine to Eradicate It

Posted by Guest Blogger on Jan 30, 2020 9:15:00 AM

This post was contributed by David Mellor from the Center for Open Science.

In the last decade, researchers have brought issues in reproducible research to the forefront in the so-called “reproducibility crisis.” Results in preclinical, biomedical and psychological sciences were called into question after credible attempts to replicate major findings could not be replicated by other researchers.There is both theoretical and empirical evidence (in psychology, cancer biology, pre-clinical life science work, economics) that published research is difficult to replicate. 

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Topics: Scientific Sharing, Reproducibility

Developing a cold tolerant E. coli using specialized chaperones

Posted by Guest Blogger on Jan 28, 2020 9:35:41 AM

This post was contributed by Sreepadmanabh M, a member of the iGEM team from IISER Bhopal.

Following up its 2018 iGEM debut - centered around a prototypical methane biosensor - IISER Bhopal is back in the SynBio arena this year with a fresh team of twenty excited undergrads. Team IISER-B’s idea for the iGEM 2019 is to take bacteria out of their optimally suited temperature ranges and make them grow better at suboptimal ones, which could allow even your regular E. coli to thrive in the bitter cold. 

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Topics: Synthetic Biology, Other

The Open Repository of CRISPR Screens: CRISPR Screen Data in One Place

Posted by Guest Blogger on Jan 21, 2020 9:30:00 AM

This post was contributed by the Open Repository of CRISPR Screens.

Imagine you’ve just discovered that your favorite gene was described in a CRISPR screen publication. You see this mentioned in the results section, but you had to dig through the supplemental files to see the actual data. Now you’re wondering if your favorite gene is included in other CRISPR screens and whether that data is useful for your research. Fortunately, there’s a growing open repository of CRISPR screen data that might be able to help you out.

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Topics: CRISPR, Other CRISPR Tools

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