Emily P. Bentley is a Blog Writer at Addgene. She earned her PhD in molecular biology and biophysics from Scripps Research, and she loves supporting open science and learning about new research.
In July, Addgene hosted a webinar titled “CRISPR Pooled Libraries: Optimizing Knockout Library Design.” If you missed it, don’t worry! Not only is it still available to watch, but this post covers the same material.
Guiding a cell through differentiation to its eventual fate requires a precise recipe of molecular signals, with transcription factors (TFs) as the key ingredients. With the right combination of TFs, scientists can also reprogram cell identity in the lab. In immune cells, such ...
iGEM isn’t any old science fair. “The world’s biggest synthetic biology competition” brings together hundreds of student teams to build projects and solve problems using molecular biology.
Check us out! This week Addgene rolled out our new brand identity, and we’re feeling sharp. We’re so excited to show you what we’ve been working on.
Do you have a green thumb — or, perhaps, are you one of those people who kills every plant they touch? The whole trouble with houseplants is they can’t bark, meow, or cry when they need something. But what if we could equip plants with a way to warn us about concerning growing ...
The genome-editing tool CRISPR is famously RNA-guided... except when it’s not. Turns out, carefully designed RNA-DNA hybrid strands work just as well—or maybe even better—at guiding Cas nucleases to specific genomic targets.
Who doesn’t love a library? A traditional library might contain thousands or millions of different books. Addgene’s pooled libraries are a little different: each is a collection of plasmids that share the same backbone and differ only in a small region. This makes them useful ...
It was huge news earlier this year: the first patient in the world, an infant, was successfully treated with a CRISPR gene editing therapy personalized to his genetic mutation. “Baby KJ” was diagnosed with a rare and dangerous metabolic disease shortly after his birth. Within a ...
