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Plasmid Tools for Microbiome Studies

Posted by Jennifer Tsang on Jun 27, 2019 8:25:58 AM

Microbiome studies have traditionally fallen into studies of who’s there and what are they doing. To address these questions, biologists often use next-generation sequencing. Sequencing the 16S rRNA reveals the identity of the organisms present while sequencing of all transcripts gives clues into what the microbes are doing.

But aside from sequencing, scientists can also study the microbiome by using engineered genetic tools and reporter microbes. Let’s take a look at a few of these methods below.

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Topics: Microbiology, Other Plasmid Tools, Plasmids

Hot Plasmids - June 2019 - Optogenetics, Acoustic Reporter Genes, microRNAs, and the CRISPR-Cas9 system CHIME

Posted by Various Addgenies on Jun 6, 2019 8:41:37 AM

Every few months we highlight a subset of the new plasmids in the repository through our hot plasmids articles. These articles provide brief summaries of recent plasmid deposits and we hope they'll make it easier for you to find and use the plasmids you need. If you'd ever like to write about a recent plasmid deposit please sign up here

 

 

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Topics: Other Plasmid Tools, Plasmids

A new platform for fast functional characterization of potentially cancerous mutations

Posted by Michael G. Lemieux on May 7, 2019 8:39:32 AM

Thousands of mutations have been implicated in cancer. Yet, the majority of them remain uncharacterized. This represents a considerable barrier to furthering research and developing effective treatments for the disease. Recently, Kenneth Scott’s lab at Baylor College of Medicine and Gordon Mills’s lab at the MD Anderson Cancer Center tackled this problem by developing a moderate throughput functional genomic platform to annotate genetic perturbations that may play significant roles in cancer pathogenesis.

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Topics: Cancer, Other Plasmid Tools, Plasmids

Hot Plasmids December 2018 - C. elegans RNAi, TurboID, Detecting Viral Outbreaks, and Protein Binding Specificity Tools

Posted by Various Addgenies on Dec 6, 2018 8:34:06 AM

Every few months we highlight a subset of the new plasmids in the repository through our hot plasmids articles. These articles provide brief summaries of recent plasmid deposits and we hope they'll make it easier for you to find and use the plasmids you need. If you'd ever like to write about a recent plasmid deposit please sign up here

Read More >

Topics: Other Plasmid Tools, Plasmids

Hot Plasmids September 2018 - Optogenetics, RNA Localization, Fluorescent Protein, and Base-editing Tools

Posted by Various Addgenies on Sep 18, 2018 9:33:20 AM

Every few months we highlight a subset of the new plasmids in the repository through our hot plasmids articles. These articles provide brief summaries of recent plasmid deposits and we hope they'll make it easier for you to find and use the plasmids you need. If you'd ever like to write about a recent plasmid deposit please sign up here.

Read More >

Topics: Other Plasmid Tools, Plasmids

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