By Maya Peters Kostman
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If you’re using CRISPR to make a genome edit, how do you know if your CRISPR experiment was successful in your organism or cell type? You can use DNA sequencing or other molecular cloning techniques to determine CRISPR/sgRNA efficiency of an experiment and confirm the correct ...
Until recently, there were no completely genetic tools that would allow researchers to label just a fraction of a single genetically-defined subset of cells. By labeling fewer cells in a population, it’s easier to visualize individual/non-overlapping cells. While transgenic ...
Last updated Jul 20, 2021. By Will Arnold and Shreya Vedantam Accelerating research by improving the availability of materials is a core part of our mission. In no situation is this more true than the current global pandemic in which scientists race to find vaccines, ...
As the world has battled the COVID-19 pandemic over the past few months, the scientific community has seen a shift towards prioritizing research into this disease. A key reason this research has been able to progress so rapidly is scientific sharing. Already we’ve seen articles ...
Adenine base editors (ABE) mediate A•T-to-G•C base changes (Figure 1), but it can be challenging to make these base changes, especially in primary human cells. Now, scientists at Beam Therapeutics have found a way to improve editing in primary human cells (Gaudelli et al., ...
This post was contributed by Shravanti Suresh from Iowa State University. Since its appearance, SARS-CoV-2 has spread to almost every part of the world manifesting as a full-fledged pandemic. Containing the spread of this virus has become an utmost priority for countries around ...
This year, Addgene welcomes three new members to the Board of Directors: Khandan Baradaran, Frank Stegmeier, and Luk Vandenberghe. We’re excited to grow the team and bring on scientists with a diverse set of experiences. Let’s meet the newest board members and get to know them!