By Ashley Waldron
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FITS In vitro CRISPR screens in immune cells have identified many putative regulators of immunity. However, in vitro screens cannot faithfully model the complex spatial, cellular, metabolic, and cytokine microenvironment that exists in vivo. Over the past five years, in vivo ...
The triple T’s of biology are transformations, transfections, and transductions! In this blog we will discuss all things transductions. If you’ve ever wondered how they are different from or similar to the other Ts, we have your answers. If you know the basics but are here ...
In the pursuit of knowledge and groundbreaking discoveries, the world of academia often emphasizes structured methodologies and rigorous research plans. However, amidst the organized chaos of lab research and PhD studies, there lies a hidden gem that has the potential to ...
As we celebrate twenty years at Addgene, we are sharing stories of our repository’s positive impact on science and scientists around the globe. Our first story focuses on a technology that has changed virtually all of biology…CRISPR.
If you take a look in a typical lab freezer, you’ll probably find lots of different plasmids containing the same protein of interest tagged with different fusion proteins for different experiments over the years — a green fluorescent protein, a red fluorescent protein, a fancy ...
Understanding the characteristics of natural plasmids and how they function in nature can inform us on how to create better recombinant vectors. In this blog post, we’ll define plasmid host range, identify a few of the features that confer broad host range in plasmids in nature, ...
Starting today, you may notice some changes to our website! Part of sharing science and making access to materials easier is improving the tools you use to share and access them. Addgene’s product, development, and content teams have made some changes to the look and feel of ...
