By Susanna Stroik
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Once upon a time, not so long ago, spCas9 was the only Cas enzyme widely available and applied by researchers for gene targeting. Fast forward a decade, and the CRISPR field has exploded with dozens of Cas enzymes and variants available. Without a comprehensive resource, it can ...
With renewed energy and optimism that comes at the start of every new year, it is a wonderful opportunity to once again reflect on our achievements in the last year and share the exciting things to come in the new year. I am proud of what we accomplished in 2023 and thrilled to ...
¡La primera edición de nuestro libro electrónico CRISPR 101 ya está disponible en español!
Annotation of genes in immune cells typically involves the creation of germline knockout mice, which is time-consuming, as it only changes one gene at a time. CRISPR-based systems enable gene knockout in immune cells in a high-throughput manner, but these systems have not been ...
Addgene is announcing we have chosen to stop all activity on X, formerly Twitter. If you are interested in engaging with us on social media, you can find us on Bluesky: @addgene.bsky.social; or @addgene on Instagram, TikTok, Facebook, and LinkedIn. We are also exploring other ...
Today marks Addgene's 20th anniversary! We've done so much in the past two (2!) decades that it's hard to summarize, but we wanted to mark the occasion by trying.
Neuromodulators like dopamine and norepinephrine have important functions in the brain but have been difficult to study without biosensors to directly visualize their activity. In 2019, the first generation of norepinephrine sensors was developed, named GRABNE, which helped ...