Embracing Serendipity: A Crucial Element in the PhD Journey

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Addgene CRISPR distribution and deposits. (A) Cumulative CRISPR plasmids shipped by year. (B) Cumulative CRISPR plasmids deposited with Addgene by year. (C) Cumulative number of laboratories that have deposited CRISPR plasmids by year. (D) Cumulative CRISPR pooled libraries shipped by year.
Four schematics of protein labeling strategies with pros and cons list for each.
Graphic showing a narrow range host plasmid with one ORI, and a broad range host plasmid with three ORIs with variable inserts.
a flow plot divided by a quadrant.
Graphic showing the three states of an integrin: Bent closed, with two proteins bent together and binding sites inaccessible; extended closed with two proteins sticking out of the extracellular matrix and one protein making an S-curve into another one, partially blocking the binding sites; and Extended-open, with both proteins sticking out of the extracellular matrix, with the protein that was bent in an s-curve now in a c-curve away from the other protein, leaving binding sites fully open.
Antibody with five example conjugation sites indicated. Each site represents a different conjugation strategy, 1) lysine 2) cysteine 3) carbohydrate 4) sequence modifications 5) protein-protein interactions.

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