Multiple Authors

Blog articles by Multiple Authors

A partial CRISPR prime editing schematic cartoon. The parts of the prime editor and pegRNA are indicated. The prime editor consists of a Cas9n H840A nickase fused to a reverse transcriptase (RT), while the pegRNA includes spacer, scaffold, RT template, and primer binding site (PBS) sequences. The desired edit is part of the RT template. In the first step, these components form a complex, bind target DNA, and nick the Cas9 non-target strand. An arrow leads to additional steps not shown in this preview.
A photograph of a firefly.

Sharing science just got easier... Subscribe to our blog