Your new antibody has arrived, hooray! Before you jump straight into the exciting new experiments that you’ve been planning, it is a good idea to pause and make sure that your antibody has been appropriately validated so that you can have confidence in your results. But what is ...
Picture this: you’ve been assigned an exciting new project aimed at understanding how a critical cellular pathway is regulated. You’ve read all the background papers you could get your hands on, formulated a hypothesis, and planned out your key experiments. Unsurprisingly, many ...
Chromatin immunoprecipitation (ChIP) is an extremely useful technique that provides insight into protein:DNA interactions. ChIP works by using antibodies to capture protein:DNA complexes with antibodies specific to your protein(s) of interest. Once the complex is captured, it is ...
You've been following along on our journey to name our new antibody mascot, who's joining us in preparation for our upcoming affinity reagent distribution launch - and we're excited to say our long naming journey is at an end! Their name is...(drum roll, please!)...
It’s not just the antibodies that matter when you’re prepping for your experiment - there are a number of outside factors that need to be considered as well. In this post, we’ll touch on antibody storage, buffer considerations, and give just the lightest of nods towards ...
If you work in a lab that regularly does immunoimaging, there’s likely a large collection of antibodies in your lab. Perhaps you’re even in that mythical place where antibodies are well-organized, documented, and easy to find (though we might need to see it to believe it.) As ...
If you’ve been following our antibody blog posts, then you likely already have a good idea of the basics of immunoimaging. A scientist conjugates an antibody with a signaling molecule, the antibody binds to a protein, and then voila! Wherever your protein of interest is, a ...
Immunoprecipitation (IP) uses immobilized antibodies, or immunoglobulins, to isolate a specific protein out of a complex mix. Using this technique, users can look for the presence or absence of a protein, determine if a protein is up or downregulated, examine a protein’s ...