Ashley Waldron is a Senior Scientist at Addgene. She loves helping researchers from around the world find, share, and learn about new tools and resources.
Imagine an antibody. Do you immediately visualize a Y-shaped protein reminiscent of the Addgene mascot Abi? If so, you are not alone. Full-sized antibodies dominate the world of research affinity reagents, and for good reason. However, sometimes you want a tool that is a little ...
The UN General Assembly has declared 2024 the International Year of Camelids. The declaration is intended to raise awareness of the economic and cultural importance of these animals to human populations around the world. Here at Addgene, we love camelids too, though not just for ...
While the antibodies present throughout our bodies carry out plenty of roles just the way they are, the research antibodies in your refrigerator often need a little help to be useful. Mainly because, well, antibodies are kind of hard to see. To solve this issue, researchers ...
Fighting with antibodies to produce immunohistochemistry images that are crisp, bright, and lacking in non-specific staining can be a challenge in the best of cases. But it can be particularly challenging when your only antibody option is from the same species as your tissue ...
Expansion Microscopy (ExM) promises an easier, more accessible way to image biological features previously only visible via techniques like super-resolution microscopy or electron microscopy. Since its introduction in 2015 by the Boyden Lab, ExM has been steadily growing in ...
Do you ever wonder about the origins of some of the common techniques or tools you use in the lab? Take for instance, the commonly used Myc-tag. Who first started using it in protein tagging experiments? Why Myc? When did the commonly used anti-c-Myc [9E10] antibody come into ...
A few months ago, we shared an introduction to immunofluorescence (IF) - a common method for visualizing molecules of interest within a cell or tissue. In that introduction, we broke down the method into six general steps and outlined the considerations to be made during each ...
Your new antibody has arrived, hooray! Before you jump straight into the exciting new experiments that you’ve been planning, it is a good idea to pause and make sure that your antibody has been appropriately validated so that you can have confidence in your results. But what is ...
