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Technique: Probe Phage Genomes for Host Binding Proteins

Posted by Guest Blogger on Sep 29, 2016 10:30:00 AM

This post was contributed by guest blogger, Jessica Sacher, a microbiology PhD student at the University of Alberta studying with the Szymanski lab.

Reasons to Study How a Phage Recognizes Its Host

Bacteriophages (viruses that prey on bacteria) may be the most numerous and most diverse biological entities on our planet, but we still know collectively little about how they infect and influence the evolution of their bacterial prey. Currently, receptor binding proteins (RBPs, the host recognition factors of phages) constitute one of the most popular classes of phage proteins to study. These are highly useful for the biotech industry, which is in the process of capitalizing on phage RBPs as diagnostic tools and therapeutics. In addition, the strategic use of whole phages as therapeutics, which is also gaining a lot of new traction lately (1, 2), depends on knowledge of the structure(s) a given phage will recognize on a host cell.

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Topics: Microbiology, Techniques, Protocols

Addgene at the ASM Microbe 2016 Conference

Posted by Jessica Welch on Jul 7, 2016 10:30:00 AM

We’ve recently begun expanding our presence in the microbiology community. For our first concrete steps into this field, we’ve curated microbiology plasmids from the repository onto one handy Microbiology Resource page and, just a few weeks ago, we attended the American Society for Microbiology's annual meeting (ASM Microbe 2016) for the first time. Our goals at the meeting were to network with scientists in this diverse and exciting field and to find out how we can serve them better. Here’s a little bit of what we learned.

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Topics: Inside Addgene, Microbiology

Introducing Addgene's Microbiology Pages

Posted by Jessica Welch on Jun 13, 2016 3:08:05 PM

Addgene will be at the American Society for Microbiology Microbe meeting here in Boston next week - be sure to come by booth #851 and say hello! Just in time for this meeting, Addgene is launching a new resource page for the Microbiology community. On our new curated Microbiology Collection page, you can browse for plasmids by species and find our guides, plasmid kits and other resources for microbial research.

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Topics: Inside Addgene, Microbiology, Plasmid Kits

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