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FPbase: A new community-editable fluorescent protein database

Posted by Guest Blogger on May 16, 2018 9:00:00 AM

This post was contributed by guest blogger Talley Lambert, a Research Associate at Harvard Medical School.

The need for a community fluorescent protein database

As recognized by the 2008 Nobel Prize, fluorescent proteins (FPs) have become one of the most indispensable tools in modern biological research.  Any microscopist will tell you that selection of a fluorescent probe (be it an organic dye or FP) is one of the most important steps in the design of an imaging experiment.  The choice is non-trivial, however, as FPs are tremendously complicated entities with a large range of characteristics (color, brightness, photostability, maturation, oligomerization), many of which are dramatically affected by environmental conditions (such as temperature, pH, fusion protein, etc...).  There are many online guides – including an excellent series of posts by Joachim Goedhart on the Addgene blog – outlining various important considerations when choosing a FP, but much of the primary data one might require when making such a decision remains spread across literature in publications that introduce these tools.

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Topics: Scientific Sharing, Fluorescent Proteins

Minisymposium on Reproducibility Livestream

Posted by Tyler Ford on May 9, 2018 10:02:54 AM

UPDATE 5/22/2018 - You can find a thorough breakdown and takeaways from the Minisymposium on reproducibility in this blog post.

 

Today at 3pm EST, we'll be discussing reproducibility issues in the biological sciences at our Minisymposium on Reproducibility. A full description of the event can be found below or on the registration page but you can view the livestream of the talks and panel here:

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Topics: Scientific Sharing, Reproducibility, Open Science

ReFigure: Save Scientific Figures into Dashboards and Share Your Insights

Posted by Guest Blogger on Dec 13, 2017 10:20:23 AM

This post was contributed by guest blogger Girija Goyal, cofounder of ReFigure.

Reading and exploration including replications and experiments resulting in “negative data” often dominate the early years of a project. Dissemination of the knowledge gained during this period occurs infrequently and rarely makes it into the small selection of data found in full-length publications. As early career researchers, we wondered how we could make the insights gained during this time more visible and thereby have a positive impact on science.

ReFigure saves time, knowledge and makes your insights discoverable. Watch this quick video to learn how ReFigure works and continue reading for more details.

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Topics: Scientific Sharing

Cultivating Community Science at BosLab

Posted by Angela Abitua on Nov 2, 2017 9:35:33 AM

Biotechnology is no longer just for those working in academia or industry. At BosLab, we identify ourselves as part of a network of independent Do-it-Yourself (DIY) biology laboratories working towards enabling everyone to participate in the biotech revolution. Our lab exists in what appears to be a funky old garage, but looks can be deceiving. Step into this building and you will find a bike kitchen on the first floor and upstairs you will find our fully-equipped laboratory for citizen scientists. In addition to maintaining a laboratory to support both individual and community science projects, we offer classes, workshops, book clubs, seminars, and social events.

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Topics: Scientific Sharing

Addgene-Seeding Labs Plasmid Grant: Accelerating Science Globally - 5 Scientists, 4 Countries & 3 Continents!

Posted by Susanna Bachle on Jul 18, 2017 8:41:28 AM

Accelerating science and supporting scientists globally are the shared mission of both Seeding Labs and Addgene. The Addgene-Seeding Labs plasmid grant is a collaborative endeavor providing plasmids to researchers in developing countries. We are proud to introduce the 5 scientists who were awarded the Addgene-Seeding Labs Plasmid grant this year. These scientists work on projects spanning from the identification of plant compounds and insecticidal proteins to the development of renewable biotechnology products and biosensors for herbicides as well as developing yeast as source for dietary supplements!

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Topics: Scientific Sharing, Investigator Feature, Seeding Labs

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