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Susanna Bachle

Susanna Bachle is an Outreach Scientist at Addgene interested in Open Science, Global Health and organizing events inside and outside Addgene. You can follow her on Twitter @SusannaMBachle.

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Plasmids 101: Visualizing Subcellular Structures & Organelles

Posted by Susanna Bachle on Jun 22, 2017 10:30:00 AM

The same way the human body is made up of organs, cells comprise compartments and structures, called organelles. Take a sneak peak inside a cell with the images from the Allen Cell Explorer (1).

When studying the function of a protein or its role in a disease, researchers often isolate proteins of interest and examine them using biochemical methods thus removing the context of the cell. However, much knowledge about functionality can be gained by understanding the location and transport of the protein within a living cell. Analyzing differences in protein localization and transport between healthy and diseased states can also provide interesting insights into disease mechanisms and protein function.

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Topics: Fluorescent Proteins

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