Susanna Bachle was formerly an Outreach Scientist at Addgene interested in Open Science, Global Health and organizing events. You can follow her on Twitter @SusannaMBachle.
Adenine base editors (ABE) mediate A•T-to-G•C base changes (Figure 1), but it can be challenging to make these base changes, especially in primary human cells. Now, scientists at Beam Therapeutics have found a way to improve editing in primary human cells (Gaudelli et al., ...
David Liu’s lab created the first base editor in 2016 (Komor et al., 2016) and since then has been trying to expand their precision editing capabilities. Base editors make specific DNA base changes and consist of a catalytically impaired Cas protein (dCas or Cas nickase) fused ...
Understanding the biology behind brain development, learning, and behavior poses many challenges in neuroscience with many brain regions, neuronal networks, and specific neuronal populations to consider. To tease apart how different neurons impact a certain output, ...
When you think about going to a scientific conference, you may think about sitting amongst a sea of chairs listening to talks all day. But nope, not at the American Society for Microbiology 2018 Microbe meeting. Soon after I arrived, I was looking through a paper-based, ...
Viruses are intracellular parasites and natural vehicles for genetic information. Therefore they make excellent tools for genetic engineering. There are several different viral vectors to choose from, for example gamma-retrovirus, lentivirus, Adenovirus, and Adeno-associated ...
A recent survey of PhDs found that many researchers feel that they lack formal training in a variety of transferable skills. At Addgene we've set out to fill this gap by both highlighting that researchers do learn MANY transferable skills while working in the lab and by offering ...
Accelerating science and supporting scientists globally are the shared mission of both Seeding Labs and Addgene. The Addgene-Seeding Labs plasmid grant is a collaborative endeavor providing plasmids to researchers in developing countries. We are proud to introduce the 5 ...
Research tackling questions in the fields of Cancer, Inflammation and Immunity, as well as various combinations thereof (so called “Immuno-Oncology”) is exploding. Researchers are increasingly able to harness the body’s immune system to fight progressing cancers. It was ...
