Alyssa is a Scientific Curator at Addgene. She received her PhD in cancer biology from Scripps Research. She loves unique animal models, all things CRISPR, and sharing science with everyone.
The versatility of CRISPR allows you to play with DNA in a number of ways, from small edits that change single base pairs, to chromosomal inversions and large deletions. Many of these methods rely on Cas9 or a derivative of Cas9, but the ever-expanding repertoire of CRISPR has ...
Forward genetics screens are a valuable part of the molecular biology toolbox to identify new target genes for drug discovery or to understand the intricacies of molecular pathways. These screens have gotten larger, easier, and more comprehensive thanks to the consistent ...
Injections in mice are a day-to-day task for many labs. Deciding which type of injection to use depends on a number of factors. You have to weigh the pros and cons of various methods and choose what is best for you — and the mice. While not an exhaustive list, these can include ...
Pre-made viruses have become increasingly accessible and are useful for saving time and avoiding potentially costly set-ups. However, there are many cases where the specific viral particles you need are not available, or the cost of custom viruses are too high for your budget. ...
Addgene is proud to present our updated CRISPR Guide!
