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Christina Mork

Christina Mork is a Scientific Curator at Addgene and loves helping turn the gears of science. She received her PhD in microbiology from Boston University and has worked as a staff scientist at the Parkinson's Institute in California.

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Behind-the-scenes of the Isolation of the Thermostable IgnaviCas9 From a Yellowstone Hot Spring

Posted by Christina Mork on Nov 12, 2019 9:00:00 AM

In 2008 the Quake Lab at Stanford University became interested in exploring biological dark matter – large tracts of the microbial tree of life that remained unexplored. Using new single-cell sequencing approaches, the lab was able to eliminate the need for axenic (pure) laboratory cultures to study these microbes. From 16S rRNA sequencing, hot springs were known to be diversity hotspots containing abundant biological dark matter and so the lab organized a sampling trip to Yellowstone National Park (YNP).

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Topics: CRISPR, Cas Proteins

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