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Searchable and Sortable gRNAs for Your Next CRISPR Experiment

Posted by Nicole Waxmonsky on May 17, 2016 10:30:00 AM

This post was written jointly by Addgenies Brook Pyhtila and Nicole Waxmonsky


Resource sharing shortens the time needed to go from planning an experiment to performing one.  At Addgene, over 120 labs have deposited CRISPR reagents, including many gRNA-containing plasmids (McDade et al, 2016). Many of the gRNAs contained within these plasmids have been used successfully in peer reviewed articles. If you’re targeting your favorite gene with CRISPR, using one of these validated gRNAs can save you the time that would be spent making and testing entirely new gRNA designs. You can now easily find many validated gRNAs in our newly curated Validated gRNA Target Sequence Table.

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Topics: Genome Engineering, Inside Addgene, CRISPR

Providing Plasmids to Researchers in Developing Countries: Addgene and Seeding Labs Team Up

Posted by Tyler Ford on Apr 5, 2016 10:30:00 AM

Researchers in developing countries often find themselves on the front lines of emerging global challenges. However, these same researchers face significant barriers to scientific discovery and career development. They are working with limited resources but limitless potential. We see it as part of our mission to enable all researchers and are proud to announce that we are teaming up with Seeding Labs to better serve those in developing countries.

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Topics: Scientific Sharing, Inside Addgene

Suggest A Plasmid You'd Like to Find at Addgene

Posted by Tyler Ford on Mar 16, 2016 1:30:00 PM


Have you ever been reading a paper and thought to yourself, “Oh! This plasmid would be perfect for my next experiment!” but were unable to find the plasmid at Addgene? Well, we’re here to help with our Suggest a Plasmid Campaign.

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Topics: Scientific Sharing, Inside Addgene

Increasing Your Work's Visibility with Addgene: Citation, Search, and Collections

Posted by Tyler Ford on Mar 10, 2016 10:30:00 AM

With many interesting articles coming out in a myriad of journals every week, it can sometimes be difficult for great work to gain prominence among all the noise. Scientists have a variety of metrics they can use to evaluate the impact of their work (H-index for instance), but these rely upon other researchers being able to find their publications in the first place. As a curator of the thousands of amazing plasmid technologies contributed by our depositors, Addgene strives to make it easier for you to find the plasmids and publications relevant to your research interests. We do this by promoting citation, supporting sophisticated search, and curating plasmid collections.

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Topics: Scientific Sharing, Inside Addgene

Call for Guest Bloggers

Posted by Tyler Ford on Mar 2, 2016 10:00:00 AM

Whenever possible, we love to give scientists the opportunity to share their knowledge. One of our goals is to be a go-to source of information on recent advances in the biological sciences and techniques that simplify and expedite research. We recognize, however, that we can’t do it all ourselves. Therefore, in this blog post we’re taking a moment to reach out to you, our readers, and ask you to share your expertise through our blog.

Do you have skill in a particular technique? Do you have a set of tips you give to every new lab mate? Do you have a trick to get the highest yield out of your minipreps? If so, we’d love to have you write for us!

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Topics: Career, Inside Addgene

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