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AAV Vector Quality Control: Going the Extra Mile with NGS

Posted by Karen Guerin on Sep 12, 2017 9:44:59 AM

Reproducible data are key to science, so scientists are used to repeating experiments to confirm their findings. But no scientist wants to repeat an experiment because of poor reagent quality. To make sure our AAV vectors are of the highest quality, we undertake a rigorous quality control process - read on to learn more!

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Topics: Viral Vectors, Inside Addgene

Plasmids 101: An Inside Look at NGS Plasmid Quality Control

Posted by Amanda Hazen on Aug 3, 2017 8:49:45 AM

All plasmids coming through Addgene’s doors are now verified by next-generation sequencing (NGS) to provide you with more data. For most plasmids, we are now able to confirm the full insert and backbone sequence. In order to manage and interpret these data, we’ve updated our quality control workflow.  Here’s a peek at how our process has improved now that we’re backed by the power of NGS!

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Topics: Plasmids 101, Inside Addgene

Improved Plasmid Maps Powered by SnapGene

Posted by Tyler Ford on Jun 29, 2017 9:06:40 AM

In meetings, in surveys, on Twitter - there is one thing we've heard over and over from our users: "Please, please improve your plasmid maps!" After thoughtful design, vetting, and tweaking, we’re excited to announce that our plasmid and sequence displays are now powered by GSL Biotech's SnapGene Server Software. With the backing of SnapGene’s sequence viewer software and extensive feature library, our updated plasmid and sequence displays are now much easier to interpret and analyze at a glance. For a quick look at just how much things have improved, check out the example below. Our old map is on the left while the SnapGene powered map is on the right (click here to see the new map in action). Read on to learn more about the improvements we’ve implemented and how they’ll make it easier for you to find the plasmids you need. We'll be monitoring and improving the maps further after this initial launch so stay tuned for more updates.

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Topics: Inside Addgene, Using Addgene's Website

Addgene's a Nonprofit? Nonprofit Awareness Day 2017

Posted by Joanne Kamens on Jun 5, 2017 11:19:13 AM

When you think of a "nonprofit" organization what do you think of? Maybe the term brings to mind a social service organization like the Red Cross or the American Cancer Society, or maybe you think about a local food pantry or community arts organization. Many people are surprised to learn that Addgene is officially filed, recognized and operated as a nonprofit under the United States Internal Revenue Code 501(c)(3). That means we were formed to benefit the public, not private interests. On this nonprofit awareness day, we layout the ways in which we promote our mission and work to enable researchers around the world.

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Topics: Inside Addgene

Activate Addgene's "Find Plasmids" Badge on Pubmed Abstracts

Posted by Caroline LaManna on May 12, 2017 8:58:59 AM

Have you ever thought - Is there an easy way to find published plasmids? Do you spend a lot of time in PubMed searching for research articles? Well then, my scientist friend, do I have a handy tool for you.  

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Topics: Inside Addgene, Scientific Sharing

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